Oxidative Stress in Chronic Kidney Disease

نویسندگان

  • Alexandra Scholze
  • Joachim Jankowski
  • José Pedraza-Chaverri
  • Pieter Evenepoel
چکیده

1Department of Nephrology, Odense University Hospital and Institute of Clinical Research, University of Southern Denmark, 5000 Odense C, Denmark 2Institute for Molecular Cardiovascular Research, RWTH Aachen University, University Hospital, 52074 Aachen, Germany 3Faculty of Chemistry, Department of Biology, National Autonomous University of Mexico (UNAM), 04510 Mexico City, Mexico 4Laboratory of Nephrology, Department of Immunology and Microbiology, University of Leuven, 3000 Leuven, Belgium

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The Effect of Regular Aerobic Training and Garlic Extract on the Oxidative and Inflammatory Indices of the Heart Tissue of Doxorubicin- induced Elderly Rats

Abstract Introduction: Heart disease is a major cause of mortality in elderly people, and oxidative stress and inflammation lead to changes in myocardium, resulting in apoptosis and cardiac hypertrophy. Accordingly, this study aimed to investigate the effect of 8 weeks of regular aerobic training along with garlic extract consumption on SOD, MDA, CAT, IL-10, and TNF-α levels in the heart tissue...

متن کامل

Antioxidant and Protective Effects of Plant Extract against Deltamethrin-induced Oxidative Stress in Liver and Kidney – A Review

Deltamethrin is one of the most commonly used Pyrethroid around the world. Oxidative stress is one of the most deltamethrin toxicity mechanisms. According to many studies, it has been shown that the liver, due to its role, is the main source of accumulation of high concentrations of deltamethrin metabolites. Also the kidney plays a very important role in regulating homeostasis of the body and r...

متن کامل

Therapeutic Effect of Deferasirox and Glycine on Chronic Cadmium Toxicosis in Rats

Objective: It has been shown that deferasirox can reduce blood and tissues lead content in animal models. In this study the effect of deferasirox alone or combined with glycine as an antioxidant was evaluated in chronic cadmium toxicosis in rat. Methods: Male wistar albino rats were exposed to 200 ppm cadmium in the drinking water for 3 weeks and treated thereafter with deferasirox (140 mg/kg),...

متن کامل

Therapeutic Effect of Deferasirox and Glycine on Chronic Cadmium Toxicosis in Rats

Objective: It has been shown that deferasirox can reduce blood and tissues lead content in animal models. In this study the effect of deferasirox alone or combined with glycine as an antioxidant was evaluated in chronic cadmium toxicosis in rat. Methods: Male wistar albino rats were exposed to 200 ppm cadmium in the drinking water for 3 weeks and treated thereafter with deferasirox (140 mg/kg),...

متن کامل

Chronic Kidney Disease Influences Multiple Systems: Describing the Relationship between Oxidative Stress, Inflammation, Kidney Damage, and Concomitant Disease

Chronic kidney disease (CKD) is characterized by increased levels of oxidative stress and inflammation. Oxidative stress and inflammation promote renal injury via damage to molecular components of the kidney. Unfortunately, relationships between inflammation and oxidative stress are cyclical in that the inflammatory processes that exist to repair radical-mediated damage may be a source of addit...

متن کامل

Oxidative stress and inflammation, a link between chronic kidney disease and cardiovascular disease.

Patients with chronic kidney disease (CKD) show a high cardiovascular morbidity and mortality. This seems to be consequence of the cardiovascular risk factor clustering in CKD patients. Non traditional risk factors such as oxidative stress and inflammation are also far more prevalent in this population than in normal subjects. Renal disease is associated with a graded increase in oxidative stre...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 2016  شماره 

صفحات  -

تاریخ انتشار 2016